-"PGP9.5 is a soluble cytoplasmic protein with a molecular weight of approximately 25,000 kD. It is present in neurons and in cells of the diffuse neuroendocrine system. PGP9.5 functions as a tissue-specific ubiquitin carboxyl terminal hydrolase isoenzyme. This enzyme is also known as UCH-L1. Because of its abundance in nerves, it has been widely used as a marker for peripheral nerve fibers
-It was also discovered as a gene mutated in some rare famial forms of Parkinson's disease. Interestingly a common allelic variant of UCHL1, the S18Y polymorphism is actually protective against Parkinson's disease. It is also a marker for cells of the diffuse neuroendocrine system and their tumors "
 
Specification:
Target: PGP9.5 [175-191]
Host: Guinea Pig (GP)
Application: Immunohistochemistry (IHC)
Product Type: Polyclonal Antiserum
Species Reactivity: Human (H), Mouse (M), Rat (R)
Format: Whole Serum (with 0.05% sodium azide) Sent in liquid form
Volumne: 50 ul & 150 ul
Immunogen Details: GASSEDTLLKDAAKVCR
                                Corresponding to residues 175-191 of soluble cytoplasmic protein
                                human PGP9.5                                
Label: Unlabeled
Antibody Type: Polyclonal